Takehiko Wada
Professor
Yasuyuki Araki
Associate Professor
Hirofumi Kurokawa
Senior Assistant Professor
Masaki Nishijima
Assistant Professor
Satoko Suzuki
Assistant Professor
Keywords
  • biomolecular chemistry
  • oligonucleotide therapeutics
  • external function controllablematerial
  • CD measurement system with high sensitivity and high time resolution

Major Grad.Sch. of Science
Web Site http://www2.tagen.tohoku.ac.jp/lab/wada/html/index.html

Design and Synthesis of Artificial Nucleic Acid and Protein for Active Control of Cellular Function and Development of High Sensitive & Time Resolve CD System

Chemical synthesis and modification of DNA/RNA and proteins are the fundamental science and technology that have led the molecular biology revolution. Hence, a chemistry of DNA/RNA and protein not only in vitro but also in vivo expects to open new generational stage of bioorganic chemistry and molecular biology. Therefore, focusing our research interest is mostly on the recognition and complexation behavior control of functional biopolymers, such as DNA/RNA, proteins, and their derivatives by external factors, toward the active control of cellular functions. Another research topics of Wada Lab. are reaction control based on molecular recognition phenomena in both the ground and electronically excited states; we are pursuing mechanistic and synthetic studies on asymmetric photo chirogenesis with supramolecular biopolymers as chiral reaction medias.

Themes

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